Beyond Nicotine. Defining Future.

Nixodine® is a cutting-edge, synthetically derived alkaloid that delivers the peak sensory experience adult consumers demand without the regulatory constraints of tobacco-derived nicotine. As the industry shifts, Nixodine® stands as the only verified, science-backed alternative capable of navigating today’s complex global legal landscape.

  • What is Nixodine®

    Nixodine®, as a leading synthetic nicotine alternative, is formulated and rigorously tested to deliver the same smooth satisfaction adult users expect from nicotine. It is not derived from tobacco or nicotine.

  • What is Nixodine® for?

    Nixodine® is intended for adult vapor consumers aged 21 and over.

    It is formulated for use in vapor products designed for adult consumers seeking an alternative to traditional nicotine products.

  • What does Nixodine® Taste Like?

    Nixodine® is almost tasteless and odorless.

    When incorporated into traditional VG/PG formulations, it enhances the experience by delivering a smoother and more refined effect.

Is Nixodine® Safe?

Bonguard Naturals, the patent and trademark holder of Nixodine®, is currently working with scientific advisors on a comprehensive white paper that will include relevant research data and Pharmacokinetic–Pharmacodynamic (PK-PD) modeling.

Nixodine® products are intended for adult nicotine consumers and adult vapers. As with any inhalable consumer product, they should be used responsibly and only by individuals of legal age.

Nixodine® products are not intended for youth, non-smokers, or individuals who do not currently use nicotine or vapor products.

Granted Patents

Issued / In Force
These are confirmed issued US patents assigned to Ready Mix Naturals, LLC:

  • Vaporizable alkaloid compositions and methods of use thereof. (Core patent for the Nixodine® family.)

  • Vaporizable alkaloid compositions and methods of use thereof.

  • Vaporizable alkaloid compositions and methods of use thereof.

  • Vaporizable alkaloid compositions and methods of use thereof.

  • Vaporizable alkaloid compsitions and methods of use thereof.

Learn more about the Patent
The List of Patents

vs

Nixodine®

Nicotine?

Contains Nicotine?


NO

YES

Fall under FDA’s Center for Tobacco Products?


NO

YES

Safety?


Potentially Less Toxic

Higher Toxicity Risks

Satisfaction?


Hits brain’s receptors (nAChRs)

Throat Hit


Mild

Harsh

Data That Tells the Future

Same Nicotinic Receptors Similar activation

X-axis: Log [Nicotine Equivalent (v/v)]

Y-axis: Receptor Activation Normalized to Nicotine

How we can help you

Exclusive Licensed Manufacturer

Superior Quality Control

Rigorous Safety Testing

Meet the Nixodine® Team

  • Mi-pod

    Nixodine® Flagship Brand
    NX Petal
    NX Blade

  • FASTA

    Nixodine® Flagship Brand
    Drop 50K
    40K Pod
    50K Pod ClearTank Ver.

  • Parfflo

    Nixodine® Flagship Brand
    All Product Integrates Nixodine.

  • Lost Mary

    MT 35K Turbo

  • Fifty Bar

    Fifty Bar 20K

  • RIFBAR

    MixPro Series

Stay Tuned …

Contact Us

If you would like to learn more about the science behind Nixodine, discuss product possibilities, or understand how to seamlessly integrate Nixodine as a nicotine replacement in your existing e-liquid or product, please reach out to us below.


WARNINGS

The statements made on this website have not been evaluated by the U.S. Food & Drug Administration (FDA). Nixodine® is not recognized as a drug in the official United States Pharmacopoeia and is not intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease. It is intended only as a satisfying alternative for adult tobacco users and vapers. Nixodine® may be addictive, may be acutely toxic and, like nicotine, should be used with caution.

⚠️ WARNINGS

UNDERAGE SALE PROHIBITED. KEEP OUT OF REACH OF CHILDREN AND PETS. USE ONLY AS DIRECTED.

Vape devices that contain Nixodine® are potentially addictive. Use with caution.

Read all of this information carefully before using vape devices that contain Nixodine®. Failure to follow these safety instructions and warnings may result in serious injury or damage. Any different use of vape devices that contain Nixodine® is at your own risk. For additional important information, review the package of any vape device your purchase.

Vapes that contain Nixodine® are not intended for pregnant or lactating women. Any individual with any known medical conditions, or taking medication(s), should consult with a licensed physician prior to using vape devices that contain Nixodine®. If a person uses any product containing Nixodine® and experiences any adverse symptoms, s/he should discontinue use of the product and immediately consult a doctor. Vape devices containing Nixodine® are for use only by current adult smokers and vapers. Vape devices containing Nixodine® are NOT smoking cessation products nor are they intended as such. If you seek to quit tobacco or nicotine use, please consult with a healthcare professional or visit www.smokefree.gov.

No vape product is safe or without risk. The risks and effects of using vape devices containing Nixodine® have not been established. Vape devices containing Nixodine®, like any vape product, can expose you to chemicals that could to cause health risks. Consult with a healthcare professional for further information.

Vape devices that contain Nixodine® can expose you to chemicals including formaldehyde, which is known to the State of California to cause cancer. For more information go to www.P65Warnings.ca.gov. Consult a healthcare professional before using vape devices that contain Nixodine® if you are using any medication. Please check the list of ingredients. This product may cause an allergic reaction.

VAPE DEVICES THAT CONTAIN NIXODINE® ARE NOT SUITABLE FOR USE BY:

  • Persons who are underage (younger than 21 years old)

  • Persons who are allergic/sensitive to propylene glycol or glycerin

  • Pregnant or breast-feeding women

  • Persons who should avoid using tobacco or vape products for medical reasons, such as persons who take medication for asthma or depression, or have heart disease, high blood pressure, diabetes, or a stomach ulcer

POSSIBLE SIDE EFFECTS:

Immediately stop use of vape devices that contain Nixodine® if you experience any of the following symptoms during or soon after use of the product:

  • Nausea

  • Coughing

  • Headache

  • Irritation in the mouth or throat

  • Nasal congestion

  • Heart palpitations

  • Vomiting

  • Abnormal heart rate

  • Stomach discomfort

  • Dizziness

  • Rash

  • Difficulty breathing

  • Chest pain

If you have any of these symptoms, or if you have any other adverse experience when using a vape device that contains Nixodine®, immediately discontinue use. If any side effects continue, seek medical assistance. Ingestion of the non-vaporized concentrated ingredients in the liquid components of vape devices that contain Nixodine® can be poisonous. If any liquid is swallowed, contact poison control or otherwise seek medical assistance immediately.

ADDITIONAL PRODUCT INFORMATION:

  • Children should never handle vape devices that contain Nixodine®

  • Do not use vape devices that contain Nixodine® around flammable liquids or gases

  • Do not use/stop using vape devices that contain Nixodine® if there is excessive leakage, discoloration, deformation, physical damage, or any other abnormality

  • The presence of dirt inside vape devices that contain Nixodine® may prevent charging, if applicable, or interfere with your enjoyment. If it’s been a while since you last used your vape device that contains Nixodine®, inspect and wipe with a clean and dry cloth if necessary

  • Do not insert any foreign object(s) or ingredient(s) into vape devices that contain Nixodine®

  • Do not tamper with or disassemble vape devices that contain Nixodine®, or attempt to refill Nixodine® vape device pods. Vape devices that contain Nixodine® do not contain any user-serviceable components.

NIXODINE® VAPE DEVICE BATTERIES SHOULD ONLY BE USED WITH THE VAPE DEVICES FOR WHICH THEY WERE INTENDED

BATTERY WARNINGS:

Nixodine® vape devices are battery-powered devices that use lithium-ion polymer batteries. Lithium-ion polymer batteries can catch fire, explode, and/or cause burns if short circuited, crushed, punctured, incinerated, disassembled, or exposed to water, fire, or high temperatures.

If applicable, only charge your Nixodine® vape battery with the supplied charging cable and do not leave the device unattended while charging. If the battery is not fully charged after 3 hours, disconnect the device and contact customer service or the retailer from whom you purchased the product.

DISPOSAL:

DO NOT dispose of any part of a Nixodine® vape device in a fire or flame. The used device should be recycled as electronic waste. Please check local regulations regarding proper disposal of electronic products and dispose of the device responsibly, using appropriate containment to avoid negative consequences on the environment and human health.

For additional information on proper disposal, please contact your local household waste disposal service or find an appropriate recycling facility.
To find a recycling drop-off location in the US, please visit www.call2recycle.org.